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NNMTi treatment combined with lean diet substitution accelerated improved body weight fat loss, increased whole-body lean mass to body weight ratio, reduced liver epididymal white adipose tissue weights, decreased liver adiposity, improved hepatic steatosis, relative to a lean diet substitution alone

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These two things combined – less vitamin B12 transferred to the baby during gestation and via breast milk – put the baby at risk for a vitamin B12 deficiency